13 peptides researched for metabolic health.
Metabolic health peptides improve how your body processes and uses energy. targeting insulin sensitivity, glucose regulation, fat oxidation, and mitochondrial function. Metabolic dysfunction underlies many chronic conditions including type 2 diabetes, cardiovascular disease, and non-alcoholic fatty liver disease.
MOTS-c is a mitochondrial-derived peptide that acts as an exercise mimetic. it activates AMPK (the same pathway triggered by exercise) and improves insulin sensitivity and glucose uptake. Semaglutide and tirzepatide, while primarily weight-loss peptides, have profound metabolic effects including improved glycemic control and reduced cardiovascular risk. AOD-9604, a modified fragment of growth hormone, targets fat metabolism specifically by stimulating lipolysis without the growth-promoting effects of full GH. These peptides work through fundamentally different mechanisms, making them complementary rather than competing approaches to metabolic health.