TB-500

Thymosin peptide · Also known as Thymosin Beta-4 fragment

What is tb-500?

A synthetic version of a naturally occurring peptide present in virtually all human cells. Known for its role in tissue repair, wound healing, and reducing inflammation.

TB-500 is a synthetic fragment of Thymosin Beta-4, a protein that plays a crucial role in cell migration, blood vessel formation, and tissue repair. It's commonly used alongside BPC-157 for enhanced recovery effects.

Key takeaway: TB-500 works through a unique mechanism of promoting cell migration to injury sites. It pairs well with BPC-157 for comprehensive recovery support.

Benefits & evidence

Wound healing Moderate confidence
Muscle recovery Moderate confidence
Anti-inflammatory Moderate confidence
Hair regrowth Preliminary confidence

How it works

TB-500 works by upregulating actin, a cell-building protein critical for cell migration and wound healing. When tissue is damaged, TB-500 helps cells move to the injury site more quickly. It also promotes blood vessel growth and reduces inflammation by downregulating inflammatory cytokines.

Dosing information

Typical dosing protocol
Starting dose

2.5 mg twice/week

Weeks 1-4 (loading)
Maintenance dose

2.5 mg twice/month

Ongoing as needed

Often cycled: 4-6 weeks loading, then maintenance dosing. Consult your healthcare provider.

Side effects

Most side effects tend to improve as your body adjusts.

Injection site redness Common
Mild headache Common
Lethargy Uncommon

Research (10 studies)

Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain. Alternative therapies in health and medicine · 2021