Growth hormone secretagogue · Also known as IPAM, Ipamorelin acetate
A selective growth hormone secretagogue that stimulates natural GH release without significantly affecting cortisol or prolactin levels.
Ipamorelin is a pentapeptide that selectively mimics ghrelin to stimulate growth hormone release from the pituitary gland. Unlike other GH secretagogues, it doesn't significantly raise cortisol, acetylcholine, prolactin, or aldosterone, making it one of the cleanest options in its class.
Ipamorelin binds to ghrelin receptors in the pituitary gland, triggering a pulse of growth hormone release that mimics the body's natural rhythm. Its selectivity means it stimulates GH without the hunger spikes associated with GHRP-6 or the cortisol increases seen with GHRP-2.
100-200 mcg 2-3x daily
4-6 weeks200-300 mcg before bed
8-12 weeksMost side effects tend to improve as your body adjusts.